Doxycycline is a commonly prescribed antibiotic for various bacterial infections. So, why do some claim that “Doxycycline ruined my life”?
Approved in 1967, this synthetic tetracycline is used to treat dental infections, eye infections, skin infections, STIs, and more. It’s also used to prevent malaria. But what are some common Doxycycline side effects? Are there significant Doxycycline health risks? Below, we take a closer look—and dig into the potential risks of this particular antibiotic. What should you know?
Common Side Effects
While Doxycycline inhibits bacterial growth and may have anti-inflammatory properties, it’s not all good news. Many say, “Doxycycline ruined my life,” because of the common side effects and complications that can arise when using this medication.
With antibiotic side effects, statistics show that all types of antibiotics may cause some level of harm. This—and due to antibiotic resistance—is why antibiotics are generally prescribed for only short lengths of time.
Specifically, Doxycycline side effects that may occur include:
- Nausea
- Vomiting
- Photosensitivity
- Upset stomach
- Loss of appetite
- Darkening of the skin
- Diarrhea
- Vaginal itching or discharge
- Skin rash
- Skin itching
About one in ten individuals who take Doxycycline will experience the above side effects. Serious side effects, on the other hand, only occur in fewer than one in 1000 individuals.
How Doxycycline Can Ruined Your Life
The severe side effects of Doxycycline may include:
- Allergic reactions: Hives, difficulty breathing, severe skin rashes, face or throat swelling, and more are all signs of a serious allergic reaction. If you experience any of these, seek out emergency medical care immediately.
- Blood or circulation problems: Signs may include unexplained bruising and bleeding, fever, or even a sore throat.
- Liver damage: All antibiotics have the potential to cause liver damage. Signs of this occurring include jaundice—yellowing of the skin or eyes. Individuals with existing liver diseases should not take Doxycycline.
- Digestive issues: Diarrhea and stomach cramps may occur. If it contains blood or mucus or lasts longer than four days, it’s important to talk with your doctor.
- Mental health complications: Anxiety is a listed side effect of Doxycycline. However, there are some rare cases of suicide when taking this antibiotic. If you notice any changes in your mood, seek out medical advice.
Long-Term Risks
It’s well-known that long-term antibiotic effects include impacting the microbiota (bacteria) in the gut and potentially having mental health repercussions. Below, we take a closer look.
Chronic Digestive Problems
Antibiotic-associated dysbiosis involves imbalances in the gut bacteria due to antibiotic use. This may lower gut microbial diversity, which is associated with a wide range of health effects (including immune and mental health repercussions). Common symptoms of this may include:
- Diarrhea
- Changes in bowel habits
- Bloating
- Bad breath
- Fatigue (often caused by poor absorption of nutrients)
This can lead to chronic digestive issues, which can take time and many adjustments in diet and lifestyle to correct. Then, there’s the link between the gut-brain axis, causing mood changes.
Mental Health Decline
Our gut health has the ability to influence how we feel and, thus, our overall mental health. If antibiotics, like Doxycycline, interfere with the balance of the gut bacteria, this can negatively affect our mood. For instance, studies note a link between dysbiosis and depression. Other research states that disruptions in gut health can even lead to the development of depression.
If left untreated or unaddressed, this can have serious and life-threatening repercussions on a person’s health and life. Again, this signifies the importance of taking antibiotics, including Doxycycline, only for a short duration.
Medical Perspective: How To Minimize the Risks
The best way to minimize the risks of Doxycycline is to take this antibiotic as directed by your healthcare provider. Generally, it should be taken with a glass of water. It can often be taken with or without food. For instance, if you find it upsets your stomach, taking Doxycycline with food may help reduce or eliminate these side effects. Additionally, the pill should be swallowed whole.
It’s further recommended to:
- Avoid iron supplements, calcium supplements, antacids, laxatives, and multivitamins within two hours before or after consuming Doxycycline.
- Avoid taking other antibiotics with Doxycycline.
- Avoiding sunlight or tanning bed exposure due to the photosensitivity this antibiotic can cause. Make sure to wear sunscreen and cover up if you go outside.
Doxycycline may also make birth control in the form of hormones less effective. When taking it, use an alternative form of birth control, such as condoms.
If you experience side effects when taking Doxycycline, some alternatives may include Minocycline or Clindamycin. However, the alternative your doctor decides upon will depend on what infection or problem is being treated with antibiotics.
Conclusion
While some claim, “Doxycycline ruined my life,” side effects and risks can be greatly reduced with proper use, as directed on the label and by your doctor. Additionally, if you experience any side effects, it’s important to discuss them with your doctor—or, if you experience serious side effects, seek out immediate emergency medical care. There are alternatives to this particular antibiotic that may be more suitable to you and your situation.
Lastly, when prescribed Doxycycline, make sure your doctor is aware of any other medications or medical conditions you may have. This can impact whether Doxycycline is right for you.
References
- https://pubmed.ncbi.nlm.nih.gov/32401726/
- https://www.nhs.uk/medicines/doxycycline/about-doxycycline/#:~:text=Doxycycline%20is%20an%20antibiotic%20that’s,sexually%20transmitted%20infections%20(STIs)
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7491661/
- https://my.clevelandclinic.org/health/articles/21655-antibiotic-resistance
- https://www.drugs.com/doxycycline.html
- https://www.nhs.uk/medicines/doxycycline/side-effects-of-doxycycline/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3888527/
- https://www.nature.com/articles/d42859-019-00019-x
- https://academic.oup.com/jid/article/223/Supplement_3/S290/6220114
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9959899/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6469458/#:~:text=The%20autonomic%20nervous%20system%2C%20hypothalamic,influence%20mood%2C%20cognition%2C%20and%20mental
- https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-024-01756-6
- https://www.drugs.com/compare/doxycycline